| MW: | 12.7kDa |
| Purity: | >95% as determined by SDS-PAGE |
| Description: | Mouse IL-13 protein, His tag (Animal-Free), expressed in HEK 293 Cells |
| Further Information: | Interleukin(IL)-13, a cytokine produced by T helper 2 (Th2) cells, is a powerful inhibitor of macrophage functions, including surface expression of CD14 and production of IL-1 and tumor necrosis factor (TNF)-alpha. Interleukin (IL) -13 synergizes with IL-2 in regulating interferon-gamma synthesis . It may be critical in regulating inflammatory and immune responses .Mouse IL-13 shares 58% sequence identity with human protein and exhibits cross-species activity.IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4. |
| NCBI EntrezGene: | 16163 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Lyophilized Mouse IL-13 protein, His tag (Animal-Free)should be stored desiccated below -20 C. Upon reconstitution, the protein should be stored at 4 C between 2-7 days and for future use below -20 C. For long term storage it is recommended to add a carrier protein (0.119% HSA or BSA). Please prevent freeze-thaw cycles. |
| Usage: | Research use only |
