| Description: | HER2/CD340 Protein, a dynamic tyrosine kinase, is crucial in neuregulin-receptor complexes and regulates microtubule dynamics. Upon activation, it triggers the MEMO1-RHOA-DIAPH1 pathway, inhibiting GSK3B and facilitating APC and CLASP2 association at the cell membrane for microtubule stabilization. In the nucleus, HER2/CD340 Protein activates PTGS2/COX-2 and rRNA genes, contributing to transcriptional regulation and protein synthesis. Its multifaceted activities emphasize its central role in cellular processes, spanning receptor signaling, microtubule dynamics, and transcriptional control. HER2/CD340 Protein, Human (Biotinylated, 142a.a, HEK293, His) is the recombinant human-derived HER2/CD340 protein, expressed by HEK293, with C-His labeled tag. The total length of HER2/CD340 Protein, Human (Biotinylated, 142a.a, HEK293, His) is 142 a.a., with molecular weight of 30-40 KDa. |
