| Description: | Beta-Catenin protein, a crucial component of the canonical Wnt pathway, regulates cellular processes. In the absence of Wnt, it complexes with AXIN1, AXIN2, APC, CSNK1A1, and GSK3B, promoting CTNNB1 phosphorylation and degradation. Upon Wnt binding, CTNNB1 accumulates in the nucleus, activating Wnt-responsive genes. Beta-Catenin also participates in cell adhesion and other functions, interacting with AXIN1, SRC, TCF7L2, and more. Its dynamic interactions highlight its role in diverse cellular functions and signaling cascades. beta-Catenin Protein, Human (sf9, His-GST) is the recombinant human-derived beta-Catenin protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. The total length of beta-Catenin Protein, Human (sf9, His-GST) is 781 a.a., with molecular weight of ~116 kDa. |
