| Description: | HER2/CD340 Protein, a versatile tyrosine kinase, is integral to neuregulin-receptor complexes and regulates microtubule dynamics. Activated HER2/CD340 triggers the MEMO1-RHOA-DIAPH1 pathway, inhibiting GSK3B at the cell membrane and facilitating APC and CLASP2 association, crucial for microtubule stabilization. In the nucleus, HER2/CD340 engages in transcriptional regulation, activating PTGS2/COX-2 and rRNA genes. Its multifaceted functions highlight its central role in cellular processes, spanning receptor signaling, microtubule dynamics, and transcriptional control. HER2/CD340 Protein, Mouse (HEK293, N-His) is the recombinant mouse-derived HER2/CD340 protein, expressed by HEK293, with N-His labeled tag. The total length of HER2/CD340 Protein, Mouse (HEK293, N-His) is 631 a.a., with molecular weight of 80-100 kDa. |
