| Description: | IFN-gamma (Interferon-gamma), a type II interferon produced by immune cells, notably T-cells and NK cells, plays pivotal roles in antimicrobial, antiviral, and antitumor responses. Operating via the JAK-STAT pathway, IFN-gamma engages its receptor IFNGR1, triggering events that lead to STAT1 activation, translocation to the nucleus, and transcription of IFN-gamma-regulated genes. Crucial in class I antigen presentation, IFN-gamma enhances peptide loading onto MHC I. Additionally, it up-regulates MHC II complexes and regulates hematopoietic stem cells, showcasing its diverse and critical functions in immune responses and hematopoiesis. IFN-gamma Protein, Mouse (HEK293) is the recombinant mouse-derived IFN-gamma protein, expressed by HEK293, with tag free. The total length of IFN-gamma Protein, Mouse (HEK293) is 133 a.a., with molecular weight of 15-21 kDa. |
