Description: | SCF Protein, a ligand for KIT receptor-type protein-tyrosine kinase, crucially regulates diverse cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinases, STAT family members, and PLCG1, producing signaling molecules. Acting with likely interleukins, SCF forms homodimers and a heterotetramer with KIT, facilitating dimerization and autophosphorylation for activation. SCF Protein, Mouse is the recombinant mouse-derived SCF protein, expressed by E. coli, with tag free. The total length of SCF Protein, Mouse is 164 a.a., with molecular weight of ~16.0 kDa. |