| Description: | Noggin, an indispensable factor in cartilage morphogenesis and joint formation, functions as a potent inhibitor of bone morphogenetic proteins (BMP) signaling, playing crucial roles in the growth and patterning of the neural tube and somite. By forming homodimers, Noggin acts as a key regulator, inhibiting chondrocyte differentiation through its interaction with growth and differentiation factors, specifically GDF5 and likely GDF6. This intricate interplay underscores Noggin's pivotal role in orchestrating essential processes in skeletal development, offering fine-tuned control over BMP signaling to ensure proper cartilage formation and overall morphogenic processes. Noggin Protein, Mouse (HEK293) is the recombinant mouse-derived Noggin protein, expressed by HEK293 , with tag free. The total length of Noggin Protein, Mouse (HEK293) is 205 a.a., with molecular weight of ~29.75 kDa. |
