Data Sheet

MSDS

Sabutoclax [CAS 1228108-65-3]

CAS No:	1228108-65-3
Applications:	Neuroscience-Neurodegeneration
MW:	700.78
Formula:	C₄₂H₄₀N₂O₈
SMILES:	O=C(C1=C(O)C(O)=CC2=C(O)[C@@]([C@@]3=C(C)C=C4C(C(NC[C@@H](C5=CC=CC=C5)C)=O)=C(O)C(O)=CC4=C3O)=C(C)C=C12)NC[C@@H](C6=CC=CC=C6)C
Purity:	99.80
Description:	Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 ?M, 0.31 ?M, 0.20 ?M, and 0.62 ?M, respectively. Sabutoclax increases Bax, Bim, PUMA and survivin expression[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only