AP-1/NF-Kappa B activation inhibitor 1 [CAS 188936-12-1] (10mM in DMSO)
Partner: MedChemexpress LLC
CAS No: | 188936-12-1 |
Applications: | COVID-19-immunoregulation |
MW: | 344.25 |
Formula: | C13H11F3N4O4 |
SMILES: | O=C(C1=CN=C(C(F)(F)F)N=C1NN2C(C(C)=CC2=O)=O)OCC |
Purity: | 99.03 |
Description: | AP-1/NF-?B activation inhibitor 1 is a potent AP-1 and NF-?B mediated transcriptional activation inhibitor (IC50=1 ?M), without blocking basal transcription driven by the ?-actin promoter. AP-1/NF-?B activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
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