Data Sheet

MSDS

MR-L2 [CAS 2374703-19-0] (10mM in DMSO)

CAS No:	2374703-19-0
Applications:	Neuroscience-Neuromodulation
MW:	441.71
Formula:	C₁₉H₁₆Cl₃FN₄O
SMILES:	ClC1=C(F)C=C(C2=NN(CC(NCC3=CC(Cl)=CC(Cl)=C3)=O)C(CC)=N2)C=C1
Purity:	99.23
Description:	MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 µM[1].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only