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Cat Number:HY-128358-1mL
Size:1mL
Price:£473.00
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Shipping:£12.00

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MR-L2 [CAS 2374703-19-0] (10mM in DMSO)

Partner: MedChemexpress LLC

CAS No:2374703-19-0
Applications:Neuroscience-Neuromodulation
MW:441.71
Formula:C19H16Cl3FN4O
SMILES:ClC1=C(F)C=C(C2=NN(CC(NCC3=CC(Cl)=CC(Cl)=C3)=O)C(CC)=N2)C=C1
Purity:99.23
Description:MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 µM[1].
Shipping Conditions:Ship on cold packs
Usage:Research Use Only

 

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