Ucf-101 [CAS 313649-08-0]
Partner: MedChemexpress LLC
| CAS No: | 313649-08-0 |
| Applications: | Neuroscience-Neurodegeneration |
| MW: | 495.51 |
| Formula: | C27H17N3O5S |
| SMILES: | O=C(/C(C(N1C2=CC=CC=C2)=O)=C/C3=CC=C(C4=C([N+]([O-])=O)C=CC=C4)O3)N(C5=CC=CC=C5)C1=S |
| Purity: | 98.06 |
| Description: | Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 ?M for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 ?M). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect[1][2][3]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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