NecroX-7 [CAS 1120332-55-9]
Partner: MedChemexpress LLC
| CAS No: | 1120332-55-9 |
| Applications: | COVID-19-immunoregulation |
| MW: | 439.57 |
| Formula: | C24H29N3O3S |
| SMILES: | O=S1(CCN(CC1)CC2=CC3=C(C(NC4CCOCC4)=C2)NC(C5=CC=CC=C5)=C3)=O |
| Purity: | 99.69 |
| Description: | NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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