Data Sheet

MSDS

Danicopan [CAS 1903768-17-1]

CAS No:	1903768-17-1
Applications:	COVID-19-immunoregulation
MW:	580.41
Formula:	C₂₆H₂₃BrFN₇O₃
SMILES:	O=C([C@H]1N(C(CN2N=C(C(C)=O)C3=C2C=CC(C4=CN=C(C)N=C4)=C3)=O)C[C@H](F)C1)NC5=NC(Br)=CC=C5
Purity:	99.91
Description:	Danicopan (ACH-4471), a selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits alternative pathway of complement (APC) activity, has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only