MRK-740 [CAS 2387510-80-5]
Partner: MedChemexpress LLC
| CAS No: | 2387510-80-5 |
| Applications: | Cancer-programmed cell death |
| MW: | 464.56 |
| Formula: | C25H32N6O3 |
| SMILES: | CC1=NC=CC(N(CC2)CCC32CN(C4=NC(C5=CC(OC)=CC(OC)=C5)=NO4)CCN3C)=C1 |
| Purity: | 99.21 |
| Description: | MRK-740 is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80?nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 (IC50?=?0.8?�M)[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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