Data Sheet

MSDS

SB-334867 (free base) [CAS 792173-99-0]

CAS No:	792173-99-0
Applications:	Neuroscience-Neuromodulation
MW:	319.32
Formula:	C₁₇H₁₃N₅O₂
SMILES:	O=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43
Purity:	99.88
Description:	SB-334867 free base (SB334867A free base) is an excellent, selective and blood�brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively[1]. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo[2][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only