JW67 [CAS 442644-28-2]
Partner: MedChemexpress LLC
| CAS No: | 442644-28-2 |
| Applications: | Cancer-programmed cell death |
| MW: | 394.38 |
| Formula: | C21H18N2O6 |
| SMILES: | O=C1C2(OCC3(COC4(C5=CC=CC=C5NC4=O)OC3)CO2)C6=CC=CC=C6N1 |
| Purity: | 98.06 |
| Description: | JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17?M[1]. JW67 affects the multiprotein complex consisting of ?-catenin/GSK-3?/AXIN/APC/CK1 that rapidly reduces active ?-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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