Motesanib [CAS 453562-69-1]
Partner: MedChemexpress LLC
CAS No: | 453562-69-1 |
Applications: | Cancer-Kinase/protease |
MW: | 373.45 |
Formula: | C22H23N5O |
SMILES: | O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3 |
Purity: | 99.96 |
Description: | Motesanib (AMG 706) is a potent ATP-competitive inhibitor of�VEGFR1/2/3�with�IC50s�of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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