Data Sheet

MSDS

PPADS (tetrasodium) [CAS 192575-19-2] (10mM in DMSO)

CAS No:	192575-19-2
Applications:	Neuroscience-Neuromodulation
MW:	599.30
Formula:	C₁₄H₁₀N₃Na₄O₁₂PS₂
SMILES:	O=S(C1=CC=C(/N=N/C2=NC(C)=C(O)C(C=O)=C2COP(O[Na])(O[Na])=O)C(S(=O)(O[Na])=O)=C1)(O[Na])=O
Purity:	95.0
Description:	PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 ?M. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca2+ exchanger in guinea pig airway smooth muscle[1][2].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only