| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 11.7 kDa (106 aa), confirmed by MALDI-TOF. |
| Purity: | > 95% by SDS - PAGE |
| Description: | Description: Glutaredoxin (GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Mammalian Glutaredoxin is known to have two isoforms, GRX1 and GRX2. GRX1 is a cytosolic protein, whereas GRX2 is localized both in the mitochondria and nucleus. Glutaredoxin-1 may be involved in a various cellular events such as signal transduction, stress response, and metabolic regulation by regulating the redox status of cellular proteins. Recombinant human Glutaredoxin1 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ |
| Synonym: | GLRX, GRX, GRX1, Thioltransferase-1, TTase-1, Glrx1, Glutaredoxin, Glutaredoxin1, Grx 1, MGC117407, Thioltransferase, Thioltransferase 1, Thioltransferase1, Ttase, TTase 1, TTase1. |
| Ascension Number: | P35754 |
| NCBI EntrezGene: | NP_002055 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
