Your Basket 0


Ordering Details

Cat Number:BNC042231-100
Concentration:0.1 mg/mL

Document Links

Data Sheet


14-3-3E/Tryptophan 5-Monooxygenase [CPTC-YWHAE-1] CF405S, Mouse Monoclonal Antibody

Partner: Biotium

Applications:IHC(p), WB
Purification:PBS, 0.1% BSA, 0.05% azide
Description:14-3-3E is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. Primary antibodies are available purified, or with a selection of fluorescent CF� Dyes and other labels. CF� Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF�405S and CF�405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Further Information:IHC, FFPE (verified)|WB (verified)
Shipping Conditions:Ship at ambient
Storage:Store at 4 C
Usage:Research Use Only


Insight Biotechnology Ltd reserves the right to change pricing without notice