| Applications: | SDS-PAGE, Bioactivity |
| Species Reactivity: | Human |
| MW: | 22.4kDa (197aa), confirmed by MALDI-TOF. |
| Purity: | > 90 % by SDS - PAGE |
| Description: | IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. IL-1alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. Recombinant human IL-1alpha was expressed in E.coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: <MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHM>SA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA |
| Synonym: | Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha: Interleukin-1a, IL-1a, Interleukin-1 alpha, IL1A, interleukin 1 alpha, IL1F1, IL-1A, preinterleukin 1 alpha, pro-interleukin-1-alpha. |
| Ascension Number: | P01583 |
| NCBI EntrezGene: | NP_000566 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoidrepeated freezing and thawing cycles. |
| Usage: | Research use only |
