| Applications: | SDS-PAGE |
| Species Reactivity: | Mouse |
| MW: | 24.6 kDa (229aa) confirmed by MALDI-TOF |
| Purity: | > 95% by SDS - PAGE |
| Description: | Blvrb, also known as flavin reductase (NADPH) isoform 1, is an enzyme (EC 1. 3. 1. 24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. Blvrb is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis. Recombinant mouse Blvrb protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTVKKIA IFGATGRTGL TTLAQAVQAG YEVTVLVRDS SRLPSEGPQP AHVVVGDVRQ AADVDKTVAG QEAVIVLLGT GNDLSPTTVM SEGTRNIVTA MKAHGVDKVV ACTSAFLLWD PTKVPPRLQD VTDDHIRMHK ILQESGLKYV AVMPPHIGDQ PLTGAYTVTL DGRGPSRVIS KHDLGHFMLR CLTTNEYDGH TTYPSHQYD |
| Synonym: | Biliverdin reductase B (flavin reductase (NADPH)), flavin reductase (NADPH) isoform 1 |
| Ascension Number: | Q923D2 |
| NCBI EntrezGene: | NP_659172 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
