Applications: | Bioactivity, SDS-PAGE |
Species Reactivity: | Mouse |
MW: | 22.5kDa (193aa) confirmed by MALDI-TOF;; 18-28kDa (SDS-PAGE under reducing conditions) |
Purity: | > 95% by SDS - PAGE |
Description: | Il6, also known as Interleukin-6, is a cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. This protein plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. Recombinant mouse Il6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Further Information: | Sequence: FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVE MRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGY NQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQR DTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEW LRTKTIQFIL KSLEEFLKVT LRSTRQTHHH HHH |
Synonym: | Interleukin-6, Il-6 |
Ascension Number: | P08505 |
NCBI EntrezGene: | NP_112445 |
Shipping Conditions: | Ship on cold packs |
Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage: | Research use only |