Ordering Details
Cat Number:	ATGP0366-100ug
Size:	100ug
Concentration:	0.5mg/mL (determined by Bradford assay)
Price:	£267.00
Quantity:
Shipping:	£12.00

PTTG1 [1-202 a.a.], Recombinant Protein

Partner: NKMax Bio (ATGen)

Applications:	SDS-PAGE
Species Reactivity:	Human
MW:	24.1 kDa (222aa), confirmed by MALDI-TOF.
Purity:	> 90% by SDS - PAGE
Description:	PTTG1, also known as Securin, is primarily involved in the regulation of sister chromatid separation during cell division. It has two identified roles; the first one is to help the transport of separase (cysteine protease) to the nucleus and the second role is to inhibit the catalytic activity of separase. It is ubiquitinated by the Anaphase Promoting Complex (APC), and then degraded by the Proteasome, releasing separase. Recombinant PTTG1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Further Information:	Sequence: MGSSHHHHHH SSGLVPRGSH MATLIYVDKE NGEPGTRVVA KDGLKLGSGP SIKALDGRSQ VSTPRFGKTF DAPPALPKAT RKALGTVNRA TEKSVKTKGP LKQKQPSFSA KKMTEKTVKA KSSVPASDDA YPEIEKFFPF NPLDFESFDL PEEHQIAHLP LSGVPLMILD EERELEKLFQ LGPPSPVKMP SPPWESNLLQ SPSSILSTLD VELPPVCCDI DI
Synonym:	Pituitary tumor-transforming protein 1, EAP1, HPTTG, PTTG, TuTR1, SECuRIN, Pituitary tumor-transforming protein 1 ESP1 ASSOCIATED PROTEIN 1, Esp1-associated protein, MGC126883, MGC138276, Pds1, PTTG1 protein, PTTG1, Pituitary tumor transforming 1, PTTG 1, EAP 1, Cut2, Pituitary tumor transforming protein 1, AW555095, Pituitary tumor-transforming 1, isoform CRA_a, Pituitary tumor-transforming 1, isoform CRA_b, hPTTG, Pituitary tumor-transforming gene 1, TuTR 1, Pttg3, Pituitary tumor-transforming gene 1 protein, C87862, TuMOR TRANSFORMING 1, Tumor transforming protein 1,
Ascension Number:	O95997
NCBI EntrezGene:	NP_004210
Shipping Conditions:	Ship on cold packs
Storage:	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage:	Research use only