| Applications: | WB, IHC-P |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. |
| Further Information: | This ABCB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-842 amino acids from the C-terminal region of human ABCB6. |
| Synonym: | ATP-binding cassette sub-family B member 6, mitochondrial, Mitochondrial ABC transporter 3, Mt-ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, ABCB6, MTABC3, PRP, UMAT |
| Ascension Number: | Q9NP58 |
| NCBI EntrezGene: | 10058 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
