Applications: | WB, IHC-P |
Species Reactivity: | Human, Mouse |
Isotype: | Rabbit Ig |
Purification: | Purified Rabbit Polyclonal Antibody |
Description: | AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia. |
Further Information: | This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from the Central region of human AASS. |
Synonym: | Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS |
Ascension Number: | Q9UDR5 |
NCBI EntrezGene: | 10157 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |