| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit Ig |
| Purification: | Affinity Purified Rabbit Polyclonal Antibody |
| Description: | This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-response element and regulates cellproliferation. The protein interacts with host cell factor C1,which also associates with the herpes simplex virus (HSV) proteinVP16 that induces transcription of HSV immediate-early genes. Thisprotein and VP16 both bind to the same site on host cell factor C1.It is thought that the interaction between this protein and hostcell factor C1 plays a role in the establishment of latency duringHSV infection. This protein also plays a role in leukocytemigration, tumor suppression, and endoplasmic reticulumstress-associated protein degradation. Additional transcriptvariants have been identified, but their biological validity hasnot been determined. |
| Further Information: | This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3. |
| Synonym: | Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP |
| Ascension Number: | O43889 |
| NCBI EntrezGene: | 10488 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
