Applications: | IHC-P-Leica, WB |
Species Reactivity: | Human |
Isotype: | Rabbit Ig |
Purification: | Affinity Purified Rabbit Polyclonal Antibody |
Description: | SIM1 and SIM2 genes are Drosophila single-minded (sim)gene homologs. SIM1 transcript was detected only in fetal kidneyout of various adult and fetal tissues tested. Since the sim geneplays an important role in Drosophila development and has peaklevels of expression during the period of neurogenesis,it wasproposed that the human SIM gene is a candidate for involvement incertain dysmorphic features (particularly the facial and skullcharacteristics), abnormalities of brain development, and/or mentalretardation of Down syndrome. |
Further Information: | This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIM1. |
Synonym: | Single-minded homolog 1, Class E basic helix-loop-helix protein 14, bHLHe14, SIM1, BHLHE14 |
Ascension Number: | P81133 |
Shipping Conditions: | Ship on cold packs |
Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
Usage: | Research use only |