| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | IgG1,? |
| Purification: | Purified Mouse Monoclonal Antibody |
| Description: | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. |
| Further Information: | This UBE2C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 137~172 amino acids from the C-terminal region of human UBE2C. |
| Synonym: | Ubiquitin-conjugating enzyme E2 C, 6.3.2.19, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C, UBE2C, UBCH10 |
| Ascension Number: | O00762 |
| NCBI EntrezGene: | 11065 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
