| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | IgG1 |
| Purification: | Mouse Monoclonal Antibody |
| Description: | This gene was identified as a locus frequently mutated inhereditary nonpolyposis colon cancer (HNPCC). It is a human homologof the E. coli DNA mismatch repair gene mutL, consistent with thecharacteristic alterations in microsatellite sequences(RER+phenotype) found in HNPCC. Alternative splicing results inmultiple transcript variants encoding distinct isoforms. Additionaltranscript variants have been described, but their full-lengthnatures have not been determined. |
| Further Information: | This MLH1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human MLH1. |
| Synonym: | DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1, COCA2 |
| Ascension Number: | P40692 |
| NCBI EntrezGene: | 4292 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
