Data Sheet

MSDS

SAP18 Polyclonal Antibody

Applications:	WB, IHC, IF
Description:	Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
Synonym:	SAP18; 2HOR0202; SAP18P; Sin3A associated protein 18
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only