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Cat Number:HY-14174-10mg
Size:10mg
Price:£239.00
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Shipping:£12.00

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MSDS

 

MRK-560 [CAS 677772-84-8]

Partner: MedChemexpress LLC

CAS No:677772-84-8
Applications:Neuroscience-Neurodegeneration
MW:517.92
Formula:C19H17ClF5NO4S2
SMILES:O=S([C@]1(C2=C(C=CC(F)=C2)F)CC[C@H](NS(C(F)(F)F)(=O)=O)CC1)(C3=CC=C(Cl)C=C3)=O
Purity:99.0
Description:MRK-560 is an orally active, brain barrier-penetrating γ-Secretase inhibitor, can potently reduce Aβ peptide in rat brain and cerebrospinal fluid. MRK-560 also decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL)[1][2].
Shipping Conditions:Ship at ambient
Usage:Research Use Only

 

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