| Applications: | WB |
| Species Reactivity: | Human |
| Isotype: | Rabbit IgG |
| Purification: | Purified Rabbit Polyclonal Antibody |
| Description: | Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. |
| Further Information: | This AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human AAK1. |
| Synonym: | AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048 |
| Ascension Number: | Q2M2I8 |
| NCBI EntrezGene: | 22848 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Maintain refrigerated at 2-8 C for up to 2 weeks. For long term storage store at -20 C in small aliquots to prevent freeze-thaw cycles. |
| Usage: | Research use only |
